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Enzymic synthesis of glucuronide metabolites
We are able to produce the metabolites required for calibration and assay testing in drug metabolism studies at a scale ranging from milligram to gram quantities.
Most of our work is done for repeat clients which include some of the largest biotechnology and pharmaceutical companies in the world.
Preparative enzymic synthesis of
glucuronide metabolites.
With key expertise in drug candidates in clinical trials, drugs of abuse, pesticides and pollutants, we can conduct fast, inexpensive feasibility studies prior to undertaking any major project in order to demonstrate proof-of-concept . We can also provide clients with accurate estimates of production costs and yields.
Our ovine or porcine liver enzyme systems enable glucuronidaton of a wide variety of compounds with correct natural stereochemistry and minimal likelihood of degradation or rearrangement.