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Drug discovery and development
IRL has specialist chemical and biochemical expertise for the discovery of new drug candidates to target a range of conditions and diseases, from malaria to cancer. We also have dedicated bioprocessing expertise for the necessary assessment of new drug candidates including impurity and identity specification and calibration and assay testing in drug metabolism studies at scales ranging from milligram to gram quantities.
Carbohydrate Chemistry R&D
IRL’s world class Carbohydrate Chemistry group offers clients a wide range of services including:
Contract R&D: The design and implementation of multi-step organic chemical syntheses to make one or a small set of small molecules (MW <1000 Daltons). As the client, you may be able to provide limited experimental methodology, or none at all, and the target structures may be defined or part of a proposed set of previously unreported structures.
Laboratory contract synthesis: Production of milligram-to-gram quantities of small molecules (MW <1000 Daltons) by multi-step organic chemical synthesis. Synthetic methods can be:
- taken from published papers, or
- client-provided recipes, or
- developed by IRL for the client.
Process development: The adaptation of laboratory-scale multi-step organic chemical synthesis procedures for use in the production of multi-kilogram batches, either under cGMP or non-GMP manufacturing conditions.
Contract processing: The production by multi-step organic chemical synthesis of 500 gram to 5 kilogram batches of materials using client-provided methodology, under non-cGMP conditions.